CCleaner will run on any PC running Microsoft Windows 7 or above. If you're running one of the following operating systems, you're fine to run CCleaner:
Since CCleaner is a small, quick program there are no minimum memory or hard drive requirements.
Note 1: For Windows NT4, ME and 98, we recommend CCleaner Version 2. For 2000 we recommend Version 3.
Note 2: CCleaner does not currently support Linux.